KCNIP3 Polyclonal Antibody | E-AB-19200

KCNIP3 Polyclonal Antibody | E-AB-19200 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 4933407H12Rik, A type potassium channel modulatory protein 3, A-type potassium channel modulatory protein 3, AI413860, Calsenilin, CSEN, CSEN, DRE antagonist modulator, DRE-antagonist modulator, DREAM, EF hand transcription factor, KCHIP 3, KChIP3, KCNIP 3, Kcnip3, Kv channel interacting protein 3, Kv channel-interacting protein 3, MGC18289, Potassium channel interacting protein 3, R74849

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Neuroscience, Signal Transduction

Background: This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3) is a Protein Coding gene. Diseases associated with KCNIP3 include Alzheimer Disease. Among its related pathways are Cardiac conduction and Development Ligand-independent activation of ESR1 and ESR2. GO annotations related to this gene include calcium ion binding and transcription corepressor activity. An important paralog of this gene is KCNIP4.

Concentration: 1.62 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Fusion protein of human KCNIP3

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A