Description
KCNQ1 Polyclonal Antibody | E-AB-15154 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: ATFB1, ATFB3, FLJ26167, IKs producing slow voltage-gated potassium channel subunit alpha, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, Jervell and Lange-Nielsen syndrome 1, JLNS1, KCNA8, KCNA9, KCNQ1, KCNQ1, kidney and cardiac voltage dependend K+ channel, KQT-like 1, Kv1.9, Kv7.1, KVLQT1, long (electrocardiographic) QT syndrome, Ward-Romano syndrome 1, LQT, LQT1, Potassium channel, voltage-gated, shaker-relatd subfamily, member 9, Potassium voltage-gated channel subfamily KQT member 1, potassium voltage-gated channel, KQT-like subfamily, member 1, RWS, slow delayed rectifier channel subunit, SQT2, Voltage-gated potassium channel subunit Kv7.1, WRS
Application: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction
Background: This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.
Concentration: 0.2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human KCNQ1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:200-1:1000, IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 75 kDa
Molecular Weight(Observed): N/A