KDM1A (1E5) monoclonal Antibody | MB0193

KDM1A (1E5) monoclonal Antibody | MB0193 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human,Monkey

Application: WB ICC IP

Application Range: WB: 1:1000 ICC: 1:100~500

Background: Lysine-specific histone demethylase 1 (LSD1), also designated BHC110, is a flavin-dependent amine oxidase which catalyzes the removal of one or two methyl groups from the methyl-lysine-4 side chain of Histone H3. The LSD1 protein contains a SWIRM domain, a FAD-binding motif and an amine oxidase domain. Association with CoREST, a SANT domain-containing corepressor, positively regulates LSD1. CoREST mediates the demethylation ability of LSD1 and protects it from proteasomal degradation in vivo.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of KDM1A and does not cross-react with related proteins.

Molecular Weight: Predicted band size:110KDa Observed band size:110KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2; KDM1A; AOF2; KDM1; KIAA0601; LSD1

Immunogen: Purified recombinant human KDM1A protein fragments expressed in E.coli.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A