Description
KHSRP monoclonal Antibody | MB9324 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human,Mouse,Rat
Application: WB FC
Application Range: WB:1:500-1:2,000 FC:1:50-1:100
Background: Binds to the dendritic targeting element and may play a role in mRNA trafficking. Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE) . May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: KHSRP monoclonal Antibody detects endogenous levels of KHSRP protein.
Molecular Weight: 73 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: FUSE-binding protein 2, KSRP, KHSRP, FUBP2, Far upstream element-binding protein 2, FBP2, FUBP2, FUBP2, FUSE binding protein 2, FUSE-binding protein 2, KH type splicing regulatory protein (FUSE binding protein 2), KH type splicing regulatory protein, KH type-splicing regulatory protein, KHSRP, KSRP, p75,
Immunogen: Synthetic peptide within human KHSRP aa 600-700.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProG purified.
Pathway: