KHSRP polyclonal Antibody | BS9961M

KHSRP polyclonal Antibody | BS9961M | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC ICC IP FC

Application Range: WB: 1:500-1:2000 ICC: 1:50-1:200 IHC: 1:50-1:200 IP: 1:10-1:50

Background: Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity) . Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single-stranded DNA from the far-upstream element (FUSE) . May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'-UTR, possibly by recruiting degradation machinery to ARE-containing mRNAs.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of KHSRP and does not cross-react with related proteins.

Molecular Weight: ~ 73 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Far upstream element-binding protein 2; FUSE-binding protein 2; KH type-splicing regulatory protein; KSRP; p75; KHSRP; FUBP2

Immunogen: Recombinant protein within human KHSRP aa 1-150.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein A affinity purified.

Pathway: