Kininogen, LMW, Human Plasma | 7301

LMW Kininogen is involved in blood pressure regulation since it is an endogenous protein substrate for tissue kallikrein. Proteolytic cleavage by kallikrein releases vasoactive bradykinin from LMW kininogen. In addition, LMW kininogen, like HMW kininogen, is a major extracellular cysteine protease inhibitor.

7301 | Kininogen LMW Human Plasma DataSheet

Biomolecule/Target: Kininogen

Synonyms: Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, High molecular weight Kininogen, Williams-Fitzgerald-Flaujeac factor, BDK, KNG, Kininogen-1 heavy chain, T-kinin, Bradykinin, Lysyl-bradykinin, Kininogen-1 light chain, Low molecular weight growth-promoting factor

Alternates names: Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, High molecular weight Kininogen, Williams-Fitzgerald-Flaujeac factor, BDK, KNG, Kininogen-1 heavy chain, T-kinin, Bradykinin, Lysyl-bradykinin, Kininogen-1 light chain, Low molecular weight growth-promoting factor

Taglines: A major extra-cellular cysteine proteinase inhibitor

NCBI Gene ID #: 20296

NCBI Gene Symbol: MCP-1

Gene Source: Human

Accession #: P10148

Recombinant: No

Source: Human Plasma

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: The activity is determined by its ability to chemoattract human monocytes at 4 - 15 ng/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 65 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 10 mM Na acetate, pH 5.5 with 200 mM NaCI

Reconstitution Instructions: Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.

Amino acid sequence: QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN