KLF1 Polyclonal Antibody | E-AB-19799

KLF1 Polyclonal Antibody | E-AB-19799 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CDAN4, EKLF, EKLF PEN, Erythroid krueppel like transcription factor (EKLF) (Erythroid transcription factor), Erythroid krueppel-like transcription factor, Erythroid Kruppel like factor, Erythroid specific transcription factor EKLF, HBFQTL6, Human erythroid-specific transcription factor EKLF mRNA complete cds, INLU, Klf1, KLF1, Krueppel-like factor 1, Kruppel like factor 1 (erythroid)

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling

Background: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.KLF1 (Kruppel Like Factor 1) is a Protein Coding gene. Diseases associated with KLF1 include Dyserythropoietic Anemia, Congenital, Type Iv and Hereditary Persistence Of Fetal Hemoglobin-Sickle Cell Disease Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is KLF4.

Concentration: 0.96 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human KLF1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:100, ELISA 1:2000-1:5000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A