KLF17 Antibody (C-term) [APR32165G]

KLF17 Antibody (C-term) [APR32165G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This KLF17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids of human KLF17.

Cellular Localisation: Nucleus.

Molecular Weight: 42577

Clone: Polyclonal

Gene Name: KLF17

Gene ID: 128209

Function: Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, FC

Dilution: WB--1:1000 FC--1:10~50

Synonyms: Krueppel-like factor 17, Zinc finger protein 393, KLF17, ZNF393