KLF4 Antibody| F40406-0.05ML/F40406-0.2ML/F41813-0.08ML/F41813-0.4ML/N1004-100UG/N1004-25UG/RQ4737

KLF4 Antibody| F40406-0.05ML/F40406-0.2ML/F41813-0.08ML/F41813-0.4ML/N1004-100UG/N1004-25UG/RQ4737 | Gentaur UK, US & Europe Distribution

Background: KLF4 is a transcription factor that can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription. [UniProt]

Format: Purified

Clone: 56CT5.1.6

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Isotype: Mouse IgG1

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, IF, FACS, ELISA

Application Details: Western blot: 1:2000, Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50

Application Note: Titration of the KLF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This KLF4 antibody is available for research use only.

Purity: Purified

Immunogen: Recombinant protein was used to produce this monoclonal KLF4 antibody.

Storage: Aliquot the KLF4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A