KLK5 | Kallikrein 5 | AS06 102

KLK5 | Kallikrein 5 | AS06 102 | Gentaur UK, US & Europe Distribution

Immunogen: KLH-conjugated mix of two synthetic peptides: one chosen from C-terminal and the other one from midregion of human KLK5 Q9Y337

Host: Rabbit

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Serum

Format: Lyophilized

Tested Application: Western blot (WB)

Related Products: AS06 101 | Anti-Kallikrein 14, rabbit antibodiesAS06 103 | Anti-pro-Kallikrein 5, rabbit antibodiesSecondary antibodies

Recommended Dilutions: 1 : 1000 (WB)

Molecular weight: 32 | 37 kDa

Confirmed Reactivity: Human

Predicted Reactivity: Human

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: Antibody is recognizing denatured active Kallikrein 5

Background: Human Kallikrein 5 (KLK5) is a serine protease produced in its inactive form. It is found in catalytically active form in stratum corneum. It has been reported to degrade desmosomes/corneodesmosomes, suggesting that it is involved in desquamtion. Egelrud et al. (2005) hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6. J Invest Dermatol, 124 (1) :198-203.Alternative names: stratum corneum tryptic enzyme, Kallikrein-like protein 2, KLK-L2

Reconstitution: For reconstitution add 200 µl of sterile water

Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Other proteins

Research Area: Cell Biology