Description
KLRG1 belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. Cell surface expression of KLRG1 is up-regulated by expression of MHC class I molecules. Recombinant human KLRG1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
7355 | KLRG1 human recombinant DataSheet
Biomolecule/Target: KLRG1
Synonyms: Killer cell lectin-like receptor subfamily G member 1, 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
Alternates names: Killer cell lectin-like receptor subfamily G member 1, 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE
Taglines: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules
NCBI Gene ID #: 6355
NCBI Gene Symbol: MCP2
Gene Source: Human
Accession #: P80075
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 99%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10-100 ng/ml.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 17 kDa (153 aa, 60-189 aa + His Tag), confirmed by MALDI-TOF.
Concentration: 0.5 mg/ml
Appearance: Liquid
Physical form description: 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.
Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1 mg/ml. This solution can be diluted into other aqueous buffers or stored at 20°C for future use.
Amino acid sequence: N/A