KLRG1, human recombinant | 7355

KLRG1 belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. Cell surface expression of KLRG1 is up-regulated by expression of MHC class I molecules. Recombinant human KLRG1 protein, fused to His-tag at N-terminus, was expressed in E.coli.

7355 | KLRG1 human recombinant DataSheet

Biomolecule/Target: KLRG1

Synonyms: Killer cell lectin-like receptor subfamily G member 1, 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE

Alternates names: Killer cell lectin-like receptor subfamily G member 1, 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE

Taglines: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules

NCBI Gene ID #: 6355

NCBI Gene Symbol: MCP2

Gene Source: Human

Accession #: P80075

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 99%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10-100 ng/ml.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 17 kDa (153 aa, 60-189 aa + His Tag), confirmed by MALDI-TOF.

Concentration: 0.5 mg/ml

Appearance: Liquid

Physical form description: 0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1 mg/ml. This solution can be diluted into other aqueous buffers or stored at –20°C for future use.

Amino acid sequence: N/A