KOR-1 (Ab-369) polyclonal Antibody | BS65124

KOR-1 (Ab-369) polyclonal Antibody | BS65124 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Monkey

Application: WB,ELISA

Application Range: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Background: opioid receptor kappa 1 (OPRK1) Homo sapiens This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jan 2016],

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: KOR-1 Polyclonal Antibody detects endogenous levels of KOR-1 protein.

Molecular Weight: ~ 48 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1

Immunogen: The antiserum was produced against synthesized peptide derived from human OPRK1. AA range:321-370

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pathway: