749
KPYR Polyclonal Antibody | ABP59073
- SKU:
- 749-ABP59073
- Availability:
- Usually ships in 5 working days
Description
KPYR Polyclonal Antibody | ABP59073 | Gentaur UK, US & Europe Distribution
Immunogen: Synthesized peptide derived from part region of human KPYR protein
Product Category: Protein
Application: Protein General Reagents
Product Type: Primary Antibody
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB, ELISA
Application Note: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000) .
Clonality: Polyclonal
Isotype: Rabbit IgG
Formulation: Liquid solution
Kit Component: N/A
Concentration: 1 mg/ml
Storage Buffer: PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Condition: Gel pack with blue ice.
Background: The Pyruvate Kinase, Liver And RBC encoded by PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA) . Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Names: Pyruvate kinase PKLR; Pyruvate kinase 1; Pyruvate kinase isozymes L/R; R-type/L-type pyruvate kinase; Red cell/liver pyruvate kinase
Precaution: The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.