KRAS Antibody| F44713-0.05ML/F44713-0.2ML

KRAS Antibody| F44713-0.05ML/F44713-0.2ML | Gentaur UK, US & Europe Distribution

Background: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human, Mouse, Rat

Predicted Spacies Reactivity: N/A

Application: WB, IF, FACS, ELISA

Application Details: Western blot: 1:500-2000, Immunofluorescence: 1:10-1:50, Flow Cytometry: 1:10-1:50

Application Note: Titration of the KRAS antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This KRAS antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 146-174 from the human protein was used as the immunogen for this KRAS antibody.

Storage: Aliquot the KRAS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A