KRAS2 Antibody (C-term) [APR31348G]

KRAS2 Antibody (C-term) [APR31348G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This KRAS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-185 amino acids from the C-terminal region of human KRAS2.

Cellular Localisation: Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol

Molecular Weight: 21656

Clone: Polyclonal

Gene Name: KRAS

Gene ID: 3845

Function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621) . Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838) . Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306) .

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras, GTPase KRas, N-terminally processed, KRAS, KRAS2, RASK2