KS-176 | B1272

KS-176 is a potent and specific inhibitor of Breast Cancer Resistance Protein (BCRP) / ATP-binding cassette sub-family G member 2 (ABCG2). Displays no inhibitory activity against P-gp or MRP1.

KS-176 is a potent and specific inhibitor of Breast Cancer Resistance Protein (BCRP) / ATP-binding cassette sub-family G member 2 (ABCG2). Displays no inhibitory activity against P-gp or MRP1.

B1272 | KS-176 DataSheet

Alternate Name/Synonyms: N-[4-(2-Hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]benzamide

Appearance: Off-white solid

Formulation: N/A

CAS Number: 1253452-78-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₁₉N₃O₅

Molecular Weight: 405.4

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>35 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and specific inhibitor of Breast Cancer Resistance Protein (BCRP) / ATP-binding cassette sub-family G member 2 (ABCG2).

MDL Number: MFCD22666402

PubChem CID: 49779726

SMILES: C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)CCO)NC(=O)C3=CC=C(C=C3)[N+](=O)[O-]

InChi: InChI=1S/C22H19N3O5/c26-14-13-15-5-9-17(10-6-15)23-22(28)19-3-1-2-4-20(19)24-21(27)16-7-11-18(12-8-16)25(29)30/h1-12,26H,13-14H2,(H,23,28)(H,24,27)

InChi Key: LTWQQWSXYYXVGA-UHFFFAOYSA-N