Kv3.2 (P626) polyclonal Antibody | BS1297

Kv3.2 (P626) polyclonal Antibody | BS1297 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels. The subunits vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming α subunits, which include the KV1, KV2, KV3, KV4 and KV9 proteins, as well as accessory subunits that modify the gating properties of the coexpressed KV subunits. KV3.2 is a multipass membrane protein that regulates the voltage-dependent K+ permeability of excitable membranes. The tail of KV3.2 may be influential in the targeting of the channel to specific subcellular compartments and/or the regulation of channel activity

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Kv3.2 (P626) polyclonal Antibody detects endogenous levels of Kv3.2 protein.

Molecular Weight: ~ 70 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Potassium voltage-gated channel subfamily C member 2; Voltage-gated potassium channel Kv3.2; KCNC2

Immunogen: Synthetic peptide, corresponding to amino acids 590-640 of Human KV3.2.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A