Description
LAG-3 Antibody [17B4] (biotin) | 36-109 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.
Research Area: Immunology, Innate Immunity
Tested Application: E
Application: ELISA: (as a detection antibody) .
Specificiy: Recognizes human LAG-3.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: 17B4
Isotype: IgG1
Conjugate: Biotin
Physical State: Liquid
Buffer: Liquid. In PBS containing 0.02% sodium azide.
Concentration: 1 mg/ml
Storage Condition: Stable for at least 1 year after receipt when stored at -20˚C.
Alternate Name: Lymphocyte Activation Gene-3; FDC Protein; CD223
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.