Laminin 2 alpha Polyclonal Antibody | BS65433

Laminin 2 alpha Polyclonal Antibody | BS65433 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,

Application: IHC-P,

Application Range: IHC-P=1:100-500

Background: Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin) . Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Laminin 2 alpha Polyclonal Antibody detects endogenous levels of Laminin 2 alpha protein.

Molecular Weight: 341kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: LAMA 2; LAMA2; LAMA2; LAMA2_HUMAN; Laminin alpha 2 (merosin congenital muscular dystrophy) ; Laminin alpha 2; Laminin alpha 2 chain; Laminin alpha 2 subunit; Laminin M; Laminin M chain; Laminin subunit alpha-2; Laminin-12 subunit alpha; Laminin-2 subunit alpha; Laminin-4 subunit alpha; LAMM; LAMM; Merosin heavy chain; Merosin heavy chain; Laminin-12 subunit alpha.

Immunogen: KLH conjugated synthetic peptide derived from human Laminin 2 alpha:2051-2200/3122

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: