LANCL2 Antibody | 8369

LANCL2 Antibody | 8369 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: LANCL2 antibody was raised against a 16 amino acid peptide from near the amino terminus of human LANCL2.
The immunogen is located within amino acids 30 - 80 of LANCL2.

Research Area: Signal Transduction

Tested Application: E, WB, IHC-P

Application: LANCL2 antibody can be used for the detection of LANCL2 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Specificiy: LANCL2 antibody is human, mouse and rat reactive.

Positive Control 1: Cat. No. 1303 - Human Brain Tissue Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 50 kDa
Observed: 48 kDa

Validation: N/A

Isoform: N/A

Purification: LANCL2 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: LANCL2 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: LANCL2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: LanC lantibiotic synthetase component C-like 2, GPR69B, LanC-like protein 2, TASP, Testis-specific adriamycin sensitivity protein

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: LANCL2 (LanC-like protein 2) , also known as TASP (testis-specific adriamycin sensitivity protein) or GPR69B, is a 450 amino acid member of the LanC-like protein family (1) . It is expressed highly in brain and testis and localized to the nucleus, cytoplasm and cell membrane (2, 3) . LANCL2 is necessary for abscisic acid (ABA) binding on the cell membrane and activation of the ABA signaling pathway in granulocytes (3, 4) .