LAQ824 | 2634

LAQ824 (Dacinostat) is a potent HDAC inhibitor (IC₅₀ = 32 nM) that displays significant activity against multiple myeloma.

LAQ824 (Dacinostat) is a potent HDAC inhibitor (IC₅₀ = 32 nM) that displays significant activity against multiple myeloma.

2634 | LAQ824 DataSheet

Alternate Name/Synonyms: (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide; Dacinostat; NVP-LAQ824

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 404951-53-7

Structure Available?: Y

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₂H₂₅N₃O₃

Molecular Weight: 379.46

Cell-Permeable?: Yes

Purity: >98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent HDAC inhibitor

MDL Number: N/A

PubChem CID: 6445533

SMILES: C1=CC=C2C(=C1)C(=CN2)CCN(CCO)CC3=CC=C(C=C3)C=CC(=O)NO

InChi: InChI=1S/C22H25N3O3/c26-14-13-25(12-11-19-15-23-21-4-2-1-3-20(19)21)16-18-7-5-17(6-8-18)9-10-22(27)24-28/h1-10,15,23,26,28H,11-14,16H2,(H,24,27)/b10-9+

InChi Key: BWDQBBCUWLSASG-MDZDMXLPSA-N