Description
LAQ824 (Dacinostat) is a potent HDAC inhibitor (IC₅₀ = 32 nM) that displays significant activity against multiple myeloma.
LAQ824 (Dacinostat) is a potent HDAC inhibitor (IC₅₀ = 32 nM) that displays significant activity against multiple myeloma.
Alternate Name/Synonyms: (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide; Dacinostat; NVP-LAQ824
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 404951-53-7
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₂H₂₅N₃O₃
Molecular Weight: 379.46
Cell-Permeable?: Yes
Purity: >98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent HDAC inhibitor
MDL Number: N/A
PubChem CID: 6445533
SMILES: C1=CC=C2C(=C1)C(=CN2)CCN(CCO)CC3=CC=C(C=C3)C=CC(=O)NO
InChi: InChI=1S/C22H25N3O3/c26-14-13-25(12-11-19-15-23-21-4-2-1-3-20(19)21)16-18-7-5-17(6-8-18)9-10-22(27)24-28/h1-10,15,23,26,28H,11-14,16H2,(H,24,27)/b10-9+
InChi Key: BWDQBBCUWLSASG-MDZDMXLPSA-N
Additional Information
Storage Condition: |
-20 ̊C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |