LATH polyclonal Antibody | BS60520

LATH polyclonal Antibody | BS60520 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: The PLUNC family of proteins are encoded by genes which map to chromosome 20 and are thought to play a potential role in the innate immune response in regions of the mouth, nose and lungs. As a member of the PLUNC family, BASE (breast cancer and salivary gland-expressed protein) is a 179 amino acid secreted protein that is named for its expression pattern. Due to its 63% sequence similarity with the related protein, Latherin, it is suggested that BASE is the major protein in sweat secretions and has important surfactant properties that lower surface tension. The expression pattern of BASE in many breast cancer cell lines suggests that it may be an easily accessible diagnostic breast cancer marker. Due to the fact that the gene encoding BASE is highly estrogen-repressed, expression of the gene is most likely dependent on HNF-3α and estrogen-mediated repression requiring ERα.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: LATH polyclonal Antibody detects endogenous levels of LATH protein.

Molecular Weight: ~ 19 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Putative BPIFA4P protein; BPI fold containing family A, member 4, pseudogene; Breast cancer and salivary gland-expressed protein; Putative latherin; BPIFA4P; BASE; LATH

Immunogen: A synthetic peptide corresponding to residues in Human LATH

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: