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LATS2 monoclonal Antibody | MB63790
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- BW-MB63790
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Description
LATS2 monoclonal Antibody | MB63790 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Mouse, Rat
Application: WB
Application Range: WB 1:2000
Background: This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]
Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Specificity: large tumor suppressor kinase 2
Molecular Weight: 120 kDa (Predicted)
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: KPM
Immunogen: Human recombinant protein fragment corresponding to amino acids 1-237 of human LATS2 (NP_055387) produced in E.coli.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway: N/A