LATS2 Polyclonal Antibody | E-AB-15942

LATS2 Polyclonal Antibody | E-AB-15942 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: FLJ13161, Kinase phosphorylated during mitosis protein, KPM, Large tumor suppressor homolog 2, Large tumor suppressor homolog 2 Drosophila, Large tumor suppressor kinase 2, LATS large tumor suppressor Drosophila homolog 2, LATS large tumor suppressor homolog 2, Lats2, LATS2, Serine/threonine kinase kpm, Serine/threonine protein kinase kpm, Serine/threonine-protein kinase kpm, Serine/threonine-protein kinase LATS2, Warts like kinase, Warts-like kinase

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling, Signal Transduction

Background: This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.

Concentration: 0.5 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human LATS2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:25-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A