LBR Polyclonal Antibody | E-AB-15166

LBR Polyclonal Antibody | E-AB-15166 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: DHCR 14B, DHCR14B, Integral nuclear envelope inner membrane protein, Lamin-B receptor, LBR, LBR, LMN 2R, LMN2R, MGC9041, PHA, PRO0650

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Metabolism, Signal Transduction, Tags and Cell Markers

Background: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Concentration: 0.4 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human LBR

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 71 kDa

Molecular Weight(Observed): N/A