Description
LBR Polyclonal Antibody | E-AB-15166 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: DHCR 14B, DHCR14B, Integral nuclear envelope inner membrane protein, Lamin-B receptor, LBR, LBR, LMN 2R, LMN2R, MGC9041, PHA, PRO0650
Application: WB, IHC, ELISA
Reactivity: Human
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Metabolism, Signal Transduction, Tags and Cell Markers
Background: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.
Concentration: 0.4 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human LBR
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 71 kDa
Molecular Weight(Observed): N/A