Description
A SMAC mimetic, potently binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP)
A SMAC mimetic, potently binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP)
Alternate Name/Synonyms: LCL-161, lcl 161, (2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propenamide, XIAP Inhibitor, IAP inhibitor
Appearance: Solid
Formulation: N/A
CAS Number: 1005342-46-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C26H33FN4O3S
Molecular Weight: 500.63
Cell-Permeable?: Yes
Purity: 99.2% by HPLC
Solubilities: Ethanol: 20 mg/ml warmed (39.94 mM); DMSO: 100 mg/ml (199.74 mM)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A SMAC mimetic and inhibitor of multiple IAPs (i.e. XIAP, c-IAP)
MDL Number: MFCD23160049
PubChem CID: 24737642
SMILES: CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C3=NC(=CS3)C(=O)C4=CC=C(C=C4)F)NC
InChi: 1S/C26H33FN4O3S/c1-16(28-2)24(33)30-22(17-7-4-3-5-8-17)26(34)31-14-6-9-21(31)25-29-20(15-35-25)23(32)18-10-12-19(27)13-11-18/h10-13,15-17,21-22,28H,3-9,14H2,1-2H3,(H,30,33)/t16-,21-,22-/m0/s1
InChi Key: UFPFGVNKHCLJJO-SSKFGXFMSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |