Description
LDE-225 diphosphate is the phosphate analog of Smoothened (Smo) antagonist LDE-225 (Cat. No. 2892).
LDE-225 diphosphate is the phosphate analog of Smoothened (Smo) antagonist LDE-225 (Cat. No. 2892).
2893 | LDE-225 diphosphate DataSheet
Alternate Name/Synonyms: N-(6-((2R,6S)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide diphosphate; Sonidegib; Erismodegib; NVP-LDE225 diphosphate
Appearance: Off-white solid
Formulation: N/A
CAS Number: 1218778-77-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₆H₃₂F₃N₃O₁₁P₂
Molecular Weight: 681.49
Cell-Permeable?: yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~10 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A potent and selective Smoothened (Smo) antagonist
MDL Number: N/A
PubChem CID: 45138699
SMILES: CC1CN(CC(O1)C)C2=NC=C(C=C2)NC(=O)C3=CC=CC(=C3C)C4=CC=C(C=C4)OC(F)(F)F.OP(=O)(O)O.OP(=O)(O)O
InChi: InChI=1S/C26H26F3N3O3.2H3O4P/c1-16-14-32(15-17(2)34-16)24-12-9-20(13-30-24)31-25(33)23-6-4-5-22(18(23)3)19-7-10-21(11-8-19)35-26(27,28)29;2*1-5(2,3)4/h4-13,16-17H,14-15H2,1-3H3,(H,31,33);2*(H3,1,2,3,4)/t16-,17+;;
InChi Key: RWIVSVMMGFFZIJ-VWDRLOGHSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |