LDE-225 diphosphate | 2893

LDE-225 diphosphate is the phosphate analog of Smoothened (Smo) antagonist LDE-225 (Cat. No. 2892).

LDE-225 diphosphate is the phosphate analog of Smoothened (Smo) antagonist LDE-225 (Cat. No. 2892).

2893 | LDE-225 diphosphate DataSheet

Alternate Name/Synonyms: N-(6-((2R,6S)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide diphosphate; Sonidegib; Erismodegib; NVP-LDE225 diphosphate

Appearance: Off-white solid

Formulation: N/A

CAS Number: 1218778-77-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₆H₃₂F₃N₃O₁₁P₂

Molecular Weight: 681.49

Cell-Permeable?: yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~10 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A potent and selective Smoothened (Smo) antagonist

MDL Number: N/A

PubChem CID: 45138699

SMILES: CC1CN(CC(O1)C)C2=NC=C(C=C2)NC(=O)C3=CC=CC(=C3C)C4=CC=C(C=C4)OC(F)(F)F.OP(=O)(O)O.OP(=O)(O)O

InChi: InChI=1S/C26H26F3N3O3.2H3O4P/c1-16-14-32(15-17(2)34-16)24-12-9-20(13-30-24)31-25(33)23-6-4-5-22(18(23)3)19-7-10-21(11-8-19)35-26(27,28)29;2*1-5(2,3)4/h4-13,16-17H,14-15H2,1-3H3,(H,31,33);2*(H3,1,2,3,4)/t16-,17+;;

InChi Key: RWIVSVMMGFFZIJ-VWDRLOGHSA-N