LDHA/LDHB polyclonal Antibody | BS90793

LDHA/LDHB polyclonal Antibody | BS90793 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat, zebrafish

Application: WB ICC/IF IHC IP FC

Application Range: WB:1:1,000-1:5,000 ICC:1:50-1:200 IHC:1:200-1:500 FC:1:50-1:100

Background: The lactate dehydrogenase family (LDH) catalyzes the final step of anaerobic glycolysis, the conversion of L-lactate and NAD to pyruvate and NADH. The LDH family consists of three members, LDH-A, LDH-B and LDH-C, all of which form tetramers consisting four subunits. However, each family member displays a specific tissue distribution pattern with LDH-A and LDH-B predominant in several tissues, specifically LDH-A in muscle and LDH-B in heart, while LDH-C expression is confined to the testis and sperm. LDHs function as powerful markers for germ cell tumors. The genes encoding human LDH-A and LDH-C map to chromosome 11, while the human LDH-B gene maps to chromosome 12. Deficiency in the LDH-A gene is linked to exertional myoglobinuria.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: LDHA/LDHB polyclonal Antibody detects endogenous levels of LDHA/LDHB protein.

Molecular Weight: 37 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: LDH-A, LDH-M, LDHA, PIG19, LDH-B, LDH-H, LDHB, Cell proliferation-inducing gene 19 protein, GSD11, L lactate dehydrogenase B chain, L-lactate dehydrogenase A chain, Lactate dehydrogenase A, Lactate dehydrogenase B, Lactate dehydrogenase H chain, Lactate dehydrogenase M, LDH A, LDH B, LDH H, LDH heart subunit, LDH M, LDH muscle subunit, LDH-A, LDH-M, LDH1, ldha, LDHA, LDHBD, LDHM, MS1111, PIG19, Proliferation inducing gene 19, Renal carcinoma antigen NY REN 46, Renal carcinoma antigen NY-REN-59, TRG 5, TRG5,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: