Leptin Antibody| F44957-0.4ML

Leptin Antibody| F44957-0.4ML | Gentaur UK, US & Europe Distribution

Background: This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq].

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse

Application: WB, IF, IHC, FACS, ELISA

Application Details: Western blot: 1:1000, Immunofluorescence: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Flow Cytometry: 1:10-1:50

Application Note: Titration of the LEP antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This LEP antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 8-37 from the human protein was used as the immunogen for this LEP antibody.

Storage: Aliquot the LEP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A