LBD
LETM1 Antibody (C-term) [APR08210G]
- SKU:
- LBD-APR08210G
- Availability:
- Usually ships in 5 working days
Description
LETM1 Antibody (C-term) [APR08210G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This LETM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 577-607 amino acids from the C-terminal region of human LETM1.
Cellular Localisation: Mitochondrion inner membrane; Single-pass membrane protein
Molecular Weight: 83354
Clone: Polyclonal
Gene Name: LETM1 (HGNC:6556)
Gene ID: 3954
Function: Mitochondrial proton/calcium antiporter that mediates proton- dependent calcium efflux from mitochondrion (PubMed:19797662) . Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain (PubMed:18628306) . Required for the maintenance of the tubular shape and cristae organization (PubMed:18628306) . In contrast to SLC8B1/NCLX, does not constitute the major factor for mitochondrial calcium extrusion (PubMed:24898248) .
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: LETM1 and EF-hand domain-containing protein 1, mitochondrial, Leucine zipper-EF-hand-containing transmembrane protein 1, LETM1