LFR polyclonal Antibody | GCP72

LFR polyclonal Antibody | GCP72 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IHC

Application Range: WB: 1:1000~1:2000 IHC: 1:50~1:200

Background: Intelectin-1, also known as ITLN1, INTL, Omentin or LFR, is a 313 amino acid protein that contains one fibrinogen C-terminal domain and is either secreted or lipid-anchored to the cell membrane. Highly expressed in small intestine and adipose tissue and present at lower levels in testis, heart, pancreas, colon and skeletal muscle, Intelectin-1 exists as a disulfide-linked homotrimer that functions to enhance Insulin-stimulated glucose uptake and is also thought to participate in host defense against miccroorganisms. In addition to its roles in glucose regulation and immune system function, Intelectin-1 may also be involved in iron metabolism and obesity regulation in adults. Intelectin-2 shares 85% amino acid identity with Intelectin-1 and, like Intelectin-1, is a secreted protein that contains one fibrinogen C-terminal domain and is thought to play a role in the host defense system. While Intelectin-1 is present in a variety of tissues, Intelectin-2 exists only in the small intestine.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: LFR polyclonal Antibody detects endogenous levels of LFR protein.

Molecular Weight: ~ 34 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Intelectin-1; ITLN-1; Endothelial lectin HL-1; Galactofuranose-binding lectin; Intestinal lactoferrin receptor; Omentin

Immunogen: Synthetic peptide, corresponding to Human LFR.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A