LHCGR Antibody | 22-092

LHCGR Antibody | 22-092 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-360 of human LHCGR (NP_000224.2) .

Research Area: Neuroscience, Signal Transduction

Tested Application: WB, IHC

Application: WB: 1:200 - 1:2000
IHC: 1:50 - 1:200

Specificiy: N/A

Positive Control 1: NCI-H460

Positive Control 2: HepG2

Positive Control 3: Jurkat

Positive Control 4: Mouse lung

Positive Control 5: Mouse ovary

Positive Control 6: Rat liver

Molecular Weight: Observed: 70-78kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: LHCGR, luteinizing hormone/choriogonadotropin receptor, LCGR, LGR2, LHR, hLHR, luteinizing hormone receptor, lutropin/choriogonadotropin receptor, LH receptor, CG receptor, LHRHR

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.