LBD
LIME1 Antibody (C-term) [APR03931G]
- SKU:
- LBD-APR03931G
- Availability:
- Usually ships in 5 working days
Description
LIME1 Antibody (C-term) [APR03931G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This LIME1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the C-terminal region of human LIME1.
Cellular Localisation: Cell membrane; Single-pass type III membrane protein Note=Present in lipid rafts. Recruited to the immunological synapse upon conjugation of T-cell with antigen-presenting cell
Molecular Weight: 31288
Clone: Polyclonal
Gene Name: LIME1
Gene ID: 54923
Function: Involved in BCR (B-cell antigen receptor) -mediated signaling in B-cells and TCR (T-cell antigen receptor) -mediated T-cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4- mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules.
Summary: Tissue Location: Expressed in peripheral blood lymphocytes, lymphoid tissues, and liver. Present in T-cells and plasma cells, and in various hematopoietic cell lines (at protein level)
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB
Dilution: WB--1:1000
Synonyms: Lck-interacting transmembrane adapter 1, Lck-interacting membrane protein, Lck-interacting molecule, LIME1, LIME