LIMS1 Polyclonal Antibody | E-AB-11365

LIMS1 Polyclonal Antibody | E-AB-11365 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 2310016J22Rik, 4921524A02Rik, AI507642, AU021743, AW551584, C430041B13Rik, LIM and senescent cell antigen like domains 1, LIM and senescent cell antigen-like-containing domain protein 1, LIM zinc finger domain containing 1, LIM-type zinc finger domains 1, Lims1, LIMS1, Lims1l, Particularly interesting new Cys His protein 1, Particularly interesting new Cys His protein, Particularly interesting new Cys-His protein 1, PINCH 1, PINCH, PINCH-1, PINCH1, Renal carcinoma antigen NY REN 48, Renal carcinoma antigen NY-REN-48, senescent cell antigen, wu:fc32c03, zgc:112533

Application: WB, IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cardiovascular, Signal Transduction

Background: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human LIMS1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 37 kDa

Molecular Weight(Observed): N/A