Lipocalin-2 polyclonal Antibody | BS90800

Lipocalin-2 polyclonal Antibody | BS90800 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB ICC/IF IHC

Application Range: WB:1:1,000-1:5,000 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:50-1:100

Background: In addition to the monomeric mammalian progelatinase, two additional forms of progelatinase have been identified. The shorter of these additional forms is a covalently linked, disulfide-bridged protein that heterodimerizes with a short protein; an α2-Microglobulin-related protein known as neutrophil gelatinase-associated lipocalin (NGAL), which is moderately expressed in breast and lung tissues. NGAL belongs to the lipocalin family and has a high degree of similarity with rat α2-Microglobulin-related protein and mouse protein 24p3. NGAL is able to bind a derivative of the bacterial chemotactic peptide, suggesting that it has important immuno-modulatory functions. NGAL has been described as an inflammatory protein; it is released into the circulation as a result of the inflammatory activation of leukocytes initiated by the extra-corporeal circulation. In addition, NGAL synthesis is induced in epithelial cells in inflammatory and neoplastic colorectal diseases. In conclusion, NGAL may serve as a scavenger of bacterial products to function in the anti-inflammatory process.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Lipocalin-2 polyclonal Antibody detects endogenous levels of Lipocalin-2 protein.

Molecular Weight: 23 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: NGAL, LCN2, 24p3, 25 kDa alpha 2 microglobulin related subunit of MMP9, 25 kDa alpha-2-microglobulin-related subunit of MMP-9, Alpha 2 microglobulin related protein, HGNC:6526, HNL, Lcn 2, Lcn2, Lipocalin-2, Migration stimulating factor inhibitor, MSFI, Neutrophil gelatinase associated lipocalin, Neutrophil gelatinase associated lipocalin precursor, Neutrophil gelatinase-associated lipocalin, NGAL, NGAL, Oncogene 24p3, Oncogenic lipocalin 24p3, p25, Siderocalin, siderocalin LCN2, SV40 induced 24P3 protein, Uterocalin,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: ProA affinity purified

Pathway: