Lisinopril dihydrate | B2132

Lisinopril is a potent angiotensin converting-Enzyme (ACE) inhibitor (IC₅₀ = 4.7 nM). The administration of lisinopril can lower the diastolic and systolic blood pressure and higher the heart rate. Lisinopril is found to reduce the activity of plasma angiotensin converting enzyme markedly. It increases the level of plasma rennin while decreases the levels of plasma Angiotensin II and aldosterone.

Lisinopril is a potent angiotensin converting-Enzyme (ACE) inhibitor (IC₅₀ = 4.7 nM). The administration of lisinopril can lower the diastolic and systolic blood pressure and higher the heart rate. Lisinopril is found to reduce the activity of plasma angiotensin converting enzyme markedly. It increases the level of plasma rennin while decreases the levels of plasma Angiotensin II and aldosterone.

B2132 | Lisinopril dihydrate DataSheet

Alternate Name/Synonyms: (S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate, Lisinopril, MK-521

Appearance: White solid

Formulation: N/A

CAS Number: 83915-83-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₃₁O₅N₃ · 2H₂O

Molecular Weight: 441.52

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: H₂O (~10 mg/ml) or DMSO (~ 5 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A potent angiotensin converting-Enzyme (ACE) inhibitor

MDL Number: MFCD01698825

PubChem CID: 5362118

SMILES: C1CC(N(C1)C(=O)C(CCCCN)NC(CCC2=CC=CC=C2)C(=O)O)C(=O)O.O.O

InChi: InChI=1S/C21H31N3O5.2H2O/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15;;/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29);2*1H2/t16-,17-,18-;;/m0../s1

InChi Key: CZRQXSDBMCMPNJ-ZUIPZQNBSA-N