Description
Lisinopril is a potent angiotensin converting-Enzyme (ACE) inhibitor (IC₅₀ = 4.7 nM). The administration of lisinopril can lower the diastolic and systolic blood pressure and higher the heart rate. Lisinopril is found to reduce the activity of plasma angiotensin converting enzyme markedly. It increases the level of plasma rennin while decreases the levels of plasma Angiotensin II and aldosterone.
Lisinopril is a potent angiotensin converting-Enzyme (ACE) inhibitor (IC₅₀ = 4.7 nM). The administration of lisinopril can lower the diastolic and systolic blood pressure and higher the heart rate. Lisinopril is found to reduce the activity of plasma angiotensin converting enzyme markedly. It increases the level of plasma rennin while decreases the levels of plasma Angiotensin II and aldosterone.
B2132 | Lisinopril dihydrate DataSheet
Alternate Name/Synonyms: (S)-1-[N2-(1-carboxy-3-phenylpropyl)-lysyl-proline dihydrate, Lisinopril, MK-521
Appearance: White solid
Formulation: N/A
CAS Number: 83915-83-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₃₁O₅N₃ · 2H₂O
Molecular Weight: 441.52
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: H₂O (~10 mg/ml) or DMSO (~ 5 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A potent angiotensin converting-Enzyme (ACE) inhibitor
MDL Number: MFCD01698825
PubChem CID: 5362118
SMILES: C1CC(N(C1)C(=O)C(CCCCN)NC(CCC2=CC=CC=C2)C(=O)O)C(=O)O.O.O
InChi: InChI=1S/C21H31N3O5.2H2O/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15;;/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29);2*1H2/t16-,17-,18-;;/m0../s1
InChi Key: CZRQXSDBMCMPNJ-ZUIPZQNBSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |