Description
LJI308 is a potent pan-RSK inhibitor, with IC₅₀ values of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.
LJI308 is a potent pan-RSK inhibitor, with IC₅₀ values of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.
Alternate Name/Synonyms: 2,6-Difluoro-4-[4-[4-(4-morpholinyl)phenyl]-3-pyridinyl]-phenol
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 1627709-94-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₁H₁₈F₂N₂O₂
Molecular Weight: 368.38
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent pan-RSK inhibitor
MDL Number: N/A
PubChem CID: 118704762
SMILES: C1COCCN1C2=CC=C(C=C2)C3=C(C=NC=C3)C4=CC(=C(C(=C4)F)O)F
InChi: InChI=1S/C21H18F2N2O2/c22-19-11-15(12-20(23)21(19)26)18-13-24-6-5-17(18)14-1-3-16(4-2-14)25-7-9-27-10-8-25/h1-6,11-13,26H,7-10H2
InChi Key: YUYJEQHNWKQNBT-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |