LLL12 | 1792

A Stat3 phosphorylation inhibitor. LLL12 inhibits STAT3 phosphorylation (Tyr705) and STAT3 activities and down-regulates STAT3 downstream targets; inhibits proliferation, colony formation, and cell migration and induces apoptosis in various human breast and pancreatic cancer cells as well as in glioblastoma cells. LLL12 has minimal apoptotic effects on normal human cells.

LLL12 is a Stat3 phosphorylation inhibitor. LLL12 inhibits STAT3 phosphorylation (Tyr705) and STAT3 activities and down-regulates STAT3 downstream targets; inhibits proliferation, colony formation, and cell migration and induces apoptosis in various human breast and pancreatic cancer cells as well as in glioblastoma cells.

1792 | LLL12 DataSheet

Alternate Name/Synonyms: 5-Hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide

Appearance: Lyophilized solid

Formulation: N/A

CAS Number: N/A

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₉NO₅S

Molecular Weight: 303.29

Cell-Permeable?: Yes

Purity: ≥95% by ¹H NMR

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A Stat3 phosphorylation inhibitor

MDL Number: N/A

PubChem CID: N/A

SMILES: N/A

InChi: N/A

InChi Key: N/A