LMAN1 monoclonal Antibody | MB63831

LMAN1 monoclonal Antibody | MB63831 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Monkey, Mouse, Rat

Application: IF, WB

Application Range: WB 1:200~500, IF 1:100

Background: The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: lectin, mannose binding 1

Molecular Weight: 54.2 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60

Immunogen: Full length human recombinant protein of human LMAN1 (NP_005561) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A