LMNA Polyclonal Antibody | E-AB-40252

LMNA Polyclonal Antibody | E-AB-40252 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 70 kDa lamin, Cardiomyopathy dilated 1A (autosomal dominant), CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, Lamin A, Lamin A/C, Lamin A/C like 1, Lamin, Lamin C, Lamin-A/C, LDP1, LFP, LGMD1B, Limb girdle muscular dystrophy 1B (autosomal dominant), LMN 1, LMN A, LMN C, LMN1, LMNA, LMNA, LMNC, LMNL1, Prelamin A/C, PRO1, Renal carcinoma antigen NY REN 32, Renal carcinoma antigen NY-REN-32, Renal carcinoma antigen NYREN32

Application: WB

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction, Tags and Cell Markers

Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Human Prelamin-A/C protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification Method: Affinity Purification

Dilution: WB 1:500-1:1000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 63, 64, 65, 69, 71, 74 kDa

Molecular Weight(Observed): 71, 74 kDa