LMO2 Antibody | 18-372

LMO2 Antibody | 18-372 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-158 of human LMO2 (NP_001135788.1) .

Research Area: Other

Tested Application: WB, IHC

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: LO2

Positive Control 2: A-549

Positive Control 3: 293T

Positive Control 4: Mouse liver

Positive Control 5: Mouse kidney

Positive Control 6: Rat liver

Molecular Weight: Observed: 18kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: LMO2, LIM domain only protein 2, LMO-2, RHOM2, RBTNL1, Rhombotin 2, Rhombotin-like 1, Cysteine-rich protein TTG-2, RBTN2, Rhombotin-2, T-cell translocation gene 2, T-cell translocation protein 2, TTG2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc) , where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.