LOC129293 Antibody (C-term) [APR03610G]

LOC129293 Antibody (C-term) [APR03610G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This LOC129293 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-371 amino acids from the C-terminal region of human LOC129293.

Cellular Localisation: Cell membrane; Single-pass type I membrane protein

Molecular Weight: 57676

Clone: Polyclonal

Gene Name: TRABD2A

Gene ID: 129293

Function: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Metalloprotease TIKI1, 34--, TRAB domain-containing protein 2A, TRABD2A, C2orf89, TIKI1