Description
Loganin is an antioxidant and cytochrome P450 substrate. Displays potent free-radical-scavenging activity. Selective β-secretase and COX-1 inhibitor. Shows neuroprotective effects against Aβ(25-35)-induced and hydrogen peroxide-induced cell death. Shows immunostimulatory, hepatoprotective and neuroprotective effects in vivo.
Loganin is an antioxidant and cytochrome P450 substrate. Displays potent free-radical-scavenging activity. Selective β-secretase and COX-1 inhibitor. Shows neuroprotective effects against Aβ(25-35)-induced and hydrogen peroxide-induced cell death. Shows immunostimulatory, hepatoprotective and neuroprotective effects in vivo.
Alternate Name/Synonyms: Loganoside; 7-Hydroxy-6-desoxyverbenalin; methyl (1S,4aS,6S,7R,7aS)-6-hydroxy-7-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylate
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 18524-94-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₂₆O₁₀
Molecular Weight: 390.4
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: H₂O
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An antioxidant and cytochrome P450 substrate.
MDL Number: MFCD00075645
PubChem CID: 87691
SMILES: CC1C(CC2C1C(OC=C2C(=O)OC)OC3C(C(C(C(O3)CO)O)O)O)O
InChi: InChI=1S/C17H26O10/c1-6-9(19)3-7-8(15(23)24-2)5-25-16(11(6)7)27-17-14(22)13(21)12(20)10(4-18)26-17/h5-7,9-14,16-22H,3-4H2,1-2H3/t6-,7+,9-,10+,11+,12+,13-,14+,16-,17-/m0/s1
InChi Key: AMBQHHVBBHTQBF-UOUCRYGSSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |