BW
LONP1 polyclonal Antibody | BS71985
- SKU:
- BW-BS71985
- Availability:
- Usually ships in 5 working days
Description
LONP1 polyclonal Antibody | BS71985 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB,IHC
Application Range: WB 1:2000 - 1:5000 IHC 1:50 - 1:200
Background: This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094) . Alternatively spliced transcript variants have been found for this gene.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: LONP1 polyclonal Antibody detects endogenous levels of LONP1 protein.
Molecular Weight: 105kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CODASS; LON; LONP; LonHS; PIM1; PRSS15; hLON
Immunogen: Recombinant protein of human LONP1
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Vesicle Trafficking presynaptic signaling,