LONP2 Antibody (N-term) [APR06181G]

LONP2 Antibody (N-term) [APR06181G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This LONP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-132 amino acids from the N-terminal region of human LONP2.

Cellular Localisation: Peroxisome matrix {ECO:0000255|HAMAP- Rule:MF_03121, ECO:0000269|PubMed:14561759, ECO:0000269|PubMed:18281296, ECO:0000269|PubMed:22002062}

Molecular Weight: 94617

Clone: Polyclonal

Gene Name: LONP2 {ECO:0000255|HAMAP-Rule:MF_03121}

Gene ID: 83752

Function: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2) -containing protein processing and facilitates peroxisome matrix protein import (By similarity) . May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.

Summary: Tissue Location: Widely expressed, with high levels in the liver, kidney and pancreas.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000

Synonyms: Lon protease homolog 2, peroxisomal {ECO:0000255|HAMAP-Rule:MF_03121}, 3421- {ECO:0000255|HAMAP-Rule:MF_03121}, Lon protease-like protein 2 {ECO:0000255|HAMAP-Rule:MF_03121}, Lon protease 2 {ECO:0000255|HAMAP-Rule:MF_03121}, Peroxisomal Lon protease {ECO:0000255|HAMAP-Rule:MF_03121}, LONP2 {ECO:0000255|HAMAP-Rule:MF_03121}, LONP